Carlos del Rio, MD Division of Infectious Diseases, Department of Internal Medicine, Emory University 

School of Medicine, Atlanta, Georgia; and Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Georgia Grady Health System, Atlanta. 

Preeti N. Malani, MD, MSJ 

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor; and 

Associate Editor,JAMA. JAMA Patient Page 

Corresponding 

Author: Carlos del Rio, MD, Emory University School of Medicine, 49 

Jesse Hill Jr Dr, FOB Room 201, Atlanta, GA 30303 ([email protected] 

emory.edu). 

Now in the third year of the coronavirus pandemic, well after the Omicron variant surge, both in the US and glob ally the number of daily cases had been declining to their lowest levels inmore than6months.While it seemed that SARS-CoV-2 was moving toward endemicity, US infec tions are again rising inMay 2022, and the reported num ber of cases is likely a gross underestimate of actual infec tions because many infections are unreported with increasingat-home testing.Several factorshelpexplain the current trends:… read more